There are a significant number of debilitating diseases where the therapeutic use of an interferon inhibitor is strongly indicated.


Click on the links to the right to learn more about some of our lead indications:




More than 5% of Americans suffer from some form of self-directed immune response.

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Approximately 800,000 people in the United States live with HIV infection.

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Trisomy 21 (Down syndrome) cells are hyper-sensitive to interferon action. We have demonstrated in a number of studies in an animal model that reducing interferon activity can reduce symptoms normally associated with trisomy 21.

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The acute and chronic rejection of transplanted organs is a serious limitation to this life-saving surgery. Our lead compound may help.

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